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Martin Mistrik Selected Research

Ditiocarb (Sodium Diethyldithiocarbamate)

3/2022One-Step Synthesis of Nanoliposomal Copper Diethyldithiocarbamate and Its Assessment for Cancer Therapy.
1/2022Cannabidiol-induced activation of the metallothionein pathway impedes anticancer effects of disulfiram and its metabolite CuET.
1/2020Targeting the NPL4 Adaptor of p97/VCP Segregase by Disulfiram as an Emerging Cancer Vulnerability Evokes Replication Stress and DNA Damage while Silencing the ATR Pathway.
12/2017Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4.

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Martin Mistrik Research Topics

Disease

13Neoplasms (Cancer)
03/2022 - 12/2008
4Alcoholism (Alcohol Abuse)
01/2022 - 12/2017
4Leukemia
01/2021 - 10/2009
4Chronic Limb-Threatening Ischemia
12/2017 - 01/2012
3Multiple Myeloma
01/2022 - 03/2013
3Prostatic Neoplasms (Prostate Cancer)
03/2021 - 11/2013
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2021 - 09/2010
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2020 - 01/2014
2Ischemia
01/2016 - 04/2013
2Cardiotoxicity
07/2015 - 02/2012
2Breast Neoplasms (Breast Cancer)
10/2012 - 12/2008
1Melanoma (Melanoma, Malignant)
03/2022
1Lymphatic Metastasis
03/2021
1Neoplasm Metastasis (Metastasis)
03/2021
1Graft vs Host Disease (Graft-Versus-Host Disease)
01/2020
1Ataxia Telangiectasia (Louis Bar Syndrome)
01/2020
1Non-alcoholic Fatty Liver Disease
01/2018
1Liver Neoplasms (Liver Cancer)
01/2018
1Xeroderma Pigmentosum (Kaposi's Disease)
12/2016
1Hemophilia A (Haemophilia)
07/2016
1Jaundice (Icterus)
05/2016
1Chronic Idiopathic Jaundice (Dubin Johnson Syndrome)
05/2016
1Hyperplasia
01/2016
1Disease Progression
01/2016
1Carcinogenesis
01/2016
1Peripheral Arterial Disease
01/2016
1Cardiovascular Diseases (Cardiovascular Disease)
07/2015
1Ovarian Neoplasms (Ovarian Cancer)
05/2015
1Pathologic Complete Response
01/2014
1Chromosome Aberrations (Chromosome Abnormalities)
01/2014
1Gangrene
04/2013

Drug/Important Bio-Agent (IBA)

7CopperIBA
03/2022 - 12/2017
7Pharmaceutical PreparationsIBA
03/2022 - 12/2017
6Biomarkers (Surrogate Marker)IBA
01/2022 - 02/2012
6Disulfiram (Antabuse)FDA Link
01/2022 - 12/2017
6Proteins (Proteins, Gene)FDA Link
03/2021 - 12/2008
4Ditiocarb (Sodium Diethyldithiocarbamate)FDA Link
03/2022 - 12/2017
3Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2019 - 10/2012
2Dexamethasone (Maxidex)FDA LinkGeneric
01/2021 - 09/2010
2DNA (Deoxyribonucleic Acid)IBA
12/2020 - 12/2016
2Phosphotransferases (Kinase)IBA
01/2020 - 02/2010
2EnzymesIBA
01/2019 - 10/2012
2pro-brain natriuretic peptide (1-76)IBA
07/2015 - 02/2012
1MetalsIBA
03/2022
1Proteasome Endopeptidase Complex (Proteasome)IBA
01/2022
1CannabidiolIBA
01/2022
1MetallothioneinIBA
01/2022
1Bortezomib (Velcade)FDA Link
01/2022
1carfilzomibIBA
01/2022
1Heavy MetalsIBA
01/2022
1Cadherins (E-Cadherin)IBA
03/2021
1ixazomibIBA
01/2021
1Lenalidomide (CC 5013)FDA Link
01/2021
1BromidesIBA
12/2020
1SurvivinIBA
12/2020
1Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA
01/2020
1Protein AggregatesIBA
01/2020
1antineoplaston A10 (A 10)IBA
01/2020
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2020
1Aldehyde DehydrogenaseIBA
10/2019
1Culture MediaIBA
10/2019
1sulfoxideIBA
10/2019
1VorinostatFDA Link
01/2019
1Histone Deacetylases (Histone Deacetylase)IBA
01/2019
1Doxorubicin (Adriamycin)FDA LinkGeneric
01/2018
1N,N-dimethylarginine (asymmetric dimethylarginine)IBA
12/2017
1Factor VIII (Coagulation Factor VIII)IBA
07/2016
1BilirubinIBA
05/2016
1PorphyrinsIBA
05/2016
1coproporphyrin IIBA
05/2016
1AntioxidantsIBA
01/2016
1Cyclin D1IBA
01/2016
1Daunorubicin (Cerubidine)FDA LinkGeneric
01/2014
1Etoposide (VP 16)FDA LinkGeneric
01/2014
1Interleukin-2 (IL2)IBA
01/2014
1Cytarabine (Cytosar-U)FDA LinkGeneric
01/2014
1Androgen Receptors (Androgen Receptor)IBA
11/2013
1polysaccharide MGN3IBA
03/2013
1arabinoxylanIBA
03/2013
1CamptothecinIBA
10/2012
1Small Interfering RNA (siRNA)IBA
10/2012
1Poly (ADP-Ribose) Polymerase-1IBA
10/2012
1Troponin T (Troponin T1)IBA
02/2012
1AnthracyclinesIBA
02/2012
1Brain Natriuretic Peptide (Natrecor)FDA Link
02/2012

Therapy/Procedure

12Therapeutics
03/2022 - 02/2010
3Stem Cell Transplantation
01/2021 - 07/2015
3Hematopoietic Stem Cell Transplantation
01/2021 - 10/2009
2Drug Therapy (Chemotherapy)
01/2022 - 01/2018
2Transplantation
01/2021 - 10/2009
1Castration
01/2019
1Limb Salvage
12/2017
1Lasers (Laser)
01/2016
1Cell- and Tissue-Based Therapy (Cell Therapy)
01/2016
1Surgical Amputation (Amputations)
01/2016
1Remission Induction
01/2014
1Combination Drug Therapy (Combination Chemotherapy)
01/2014
1Radiotherapy
11/2013
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
04/2013
1Cell Transplantation
04/2013